Do NOT use Nolvadex if:
you are allergic to any ingredient in Nolvadex
you are using Nolvadex to reduce your risk of breast cancer and you have a history of blood clots in the lung or leg
you are using Nolvadex to reduce your risk of breast cancer and you also take certain anticoagulants (eg, warfarin)
you are taking anastrozole
Contact your doctor or health care provider right away if any of these apply to you.
Before using Nolvadex:
Some medical conditions may interact with Nolvadex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of blood clots in the legs or lungs
if you have high levels of calcium in your blood, a weakened immune system, or low levels of white blood cells or platelets in your blood
if you have high cholesterol or lipid levels
if you have cataracts or other vision problems
if you are using cytotoxic cancer medicines
if you are confined to a bed or chair
Some MEDICINES MAY INTERACT with Nolvadex. Tell your health care provider if you are taking any other medicines, especially any of the following:
Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
Cytotoxic cancer medicines (eg, cisplatin) because the risk of developing blood clots may be increased
Rifampin because it may decrease Nolvadex's effectiveness
Fluorouracil or mitomycin C because they may increase the risk of Nolvadex's side effects
Aromatase inhibitors (eg, anastrozole, letrozole) because their effectiveness may be decreased by Nolvadex
This may not be a complete list of all interactions that may occur. Ask your health care provider if Nolvadex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Nolvadex:
Use Nolvadex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Nolvadex comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nolvadex refilled.
Nolvadex may be taken by mouth with or without food.
Take Nolvadex with water or another nonalcoholic liquid.
Swallow this medication whole. Do not break, crush, or chew before swallowing.
Continue to take Nolvadex even if you feel well. Do not miss any doses. Taking Nolvadex at the same time each day will help you to remember to take it.
If you miss a dose of Nolvadex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Nolvadex.
Possible side effects of Nolvadex:
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Bone pain; constipation; coughing; hot flashes; muscle pain; nausea; tiredness; vaginal discharge; weight loss.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unexplained hoarseness); abnormal menstrual periods; abnormal vaginal bleeding or bloody discharge; chest pain; coughing up blood; dark urine; decreased sexual desire or ability; depression; fever, chills, or persistent sore throat; groin or pelvic pain or pressure; loss of appetite; loss of balance or coordination; missed menstrual period; new or increased breast tumor or pain; new or unusual lumps; one-sided weakness; pain or swelling in one or both legs; red, swollen, blistered, or peeling skin; severe or persistent tiredness or weakness; shortness of breath; skin changes; stomach pain; sudden severe headache; swelling of the arms or the legs; unusual bleeding or bruising; vision or speech problems; yellowing of the eyes or skin.

